Disease

Alzheimer’s Disease (ad)

2 developments in the corpus

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JUN 26, 2026 · JOURNAL ARTICLE

Systemic infections alter cortical transcriptional signatures in Alzheimer's disease.

Neurobiology of Aging

Post-mortem observational study with transcriptomic analysis identifies associations between infection status and gene expression patterns in AD brain tissue, but lacks experimental validation, longitudinal data, or causal evidence to support clinical intervention.

PreliminaryAlzheimer’s Disease (ad)Lachlan F MacBean Katie Lunnon

Reported

Sample size202

AD donors113

Control donors89

JAN 9, 2026 · JOURNAL ARTICLE

Targeting CXCL8 in post-traumatic stress disorder and Alzheimer's disease: insights from cross-disorder molecular analysis.

Annals of Medicine

Bioinformatics and computational analysis identifying CXCL8 as a shared molecular target in PTSD and Alzheimer's disease, with limited experimental validation and no clinical trial data.

PreliminaryTianjing Li Alzheimer’s Disease (ad)Micrornas

Reported

PTSD sample size109

Alzheimer's disease sample size116

PTSD treatment resistance rate30%