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Marius Păpurică

Victor Babeș University of Medicine and Pharmacy Timișoara

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AUG 11, 2026 · JOURNAL ARTICLE

Survival and Pathologic Response After Neoadjuvant Treatment in Esophagogastric Cancer

Diagnostics

Systematic review of 60 studies (18 RCTs, 42 cohorts) with consistent evidence that pathological response predicts survival in neoadjuvant-treated esophagogastric cancer, though high clinical heterogeneity limits direct practice guidance.

Strong EvidenceMarius Păpurică Gabriel-Petre Gorecki Claudiu-Rafael Bârsac

Reported

pCR range across regimens8% to 49%

Mean pCR with CRT33%

Mean major TRG response with CRT63%

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