AUG 11, 2026 · JOURNAL ARTICLE
Early EGFR inhibition triggers actionable tumour and microenvironmental remodelling in lung cancer
Cancer Research Communications
Single-arm neoadjuvant study with comprehensive molecular profiling showing early tumour and microenvironmental changes, but limited by small sample size, lack of control arm, and surrogate endpoints rather than hard clinical outcomes.
Reported
Objective response rate62%
Disease control rate100%
Pathological downstaging rate46%