SEP 5, 2026 · JOURNAL ARTICLE
Targeting the Fatty Acid Binding Protein 5–Specificity Protein 1 Axis Restores Enzalutamide Sensitivity by Suppressing Androgen Receptor/Androgen Receptor Splice Variant 7 Signaling: Implications for Prostate Cancer Therapy
World Journal of Oncology
Mechanistic study in cell culture identifying a putative regulatory axis; lacks clinical validation, patient outcomes, or prospective testing needed to support therapeutic claims.
Study details
DesignIn vitro mechanistic study with correlative…
InterventionFABP5 genetic ablation or overexpression; S…
ComparatorBaseline/control cells; wild-type genotype