Virulence

OCT 19, 2026 · JOURNAL ARTICLE

Single-cell transcriptomic atlas uncovers immune/structural lineage remodeling and fibrosis in Klebsiella pneumoniae-infected porcine lungs.

Virulence

Klebsiella pneumoniae (KP) is a predominant pathogen in respiratory infections, whose widespread antibiotic resistance poses severe public health risks and economic burdens. As the

OCT 16, 2026 · JOURNAL ARTICLE

Subverting colonization resistance: Salmonella pathogenesis at the interface of microbiota, metabolism and inflammasome.

Virulence

The intestinal tract is a key immune organ and microecological system, where colonization resistance (CR) mediated by gut microbiota prevents pathogen invasion. Salmonella disrupts

OCT 15, 2026 · JOURNAL ARTICLE

Itaconate as an immunometabolic hub in host-pathogen interactions: Mechanisms, resistance, and therapeutic opportunities.

Virulence

Produced by IRG1 in macrophages, itaconate has emerged as an immunometabolic hub at the host-pathogen interface. This review integrates itaconate's roles in antimicrobial defense.

OCT 12, 2026 · JOURNAL ARTICLE

Pathogenicity and virulence of Giardia intestinalis.

Virulence

Giardiasis, caused by Giardia intestinalis, is a prevalent intestinal protozoan infection worldwide. Clinical manifestations are variable, and many infections remain asymptomatic.

SEP 27, 2026 · JOURNAL ARTICLE

Exploiting virulence determinants for precision management of melioidosis: A multi-omics roadmap from pathogenesis to point-of-care: A perspective review.

Virulence

Melioidosis, caused by Burkholderia pseudomallei, remains challenging to diagnose promptly, partly due to limited use of virulence factors as diagnostic targets. Most existing biom

SEP 23, 2026 · JOURNAL ARTICLE

Comparative pathogenicity study of monkeypox virus Clade Ib and Clade IIb in a rabbit model.

Virulence

Mpox has emerged as a significant public health concern, spreading across continents with the emergence of new variants. Clade IIb, from the recent global outbreak, and the newly i

SEP 15, 2026 · JOURNAL ARTICLE

Prevotella intermedia culture supernatant impairs alveolar macrophage function and promotes Mycobacterium avium persistence.

Virulence

Microbiome analyses using 16S ribosomal RNA gene sequencing have revealed a higher prevalence of Prevotella species in patients with nontuberculous mycobacterial pulmonary disease

SEP 14, 2026 · JOURNAL ARTICLE

Rethinking the immune recognition of cell walls in human fungal pathogens: Mechanisms, controversies and translational significance.

Virulence

Fungal cell wall polysaccharides - such as β-glucans, chitin, and mannans - are key immunogenic structures recognized by Toll-like receptors and C-type lectin receptors on innate i