OCT 26, 2026 · JOURNAL ARTICLE
Profound Radiographic and Tumor-Lytic Response of Locally Advanced Pancreatic Adenocarcinoma to a Non-Systemic-Chemotherapy Multimodal Protocol—Fractionated Radiotherapy with Capecitabine Radiosensitization, Intratumoral EpCAM/CD3 Bispecific Antibody, Allogeneic NK and Autologous Lymphocyte Cellular Therapy, and Sequenced Pembrolizumab Following Failure of Conventional Gemcitabine-Based Therapy
Translational Insights
Introduction: Locally advanced pancreatic adenocarcinoma (LAPC) carries a dismal prognosis with conventional therapy. Patients who progress on or plateau after first-line gemcitabi