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OCT 18, 2026 · JOURNAL ARTICLE

DNA Nanostructures for Overcoming Cancer Drug Resistance: Mechanisms, Therapeutic Strategies, and Translational Challenges

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ABSTRACT Cancer drug resistance, a major cause of chemotherapy failure, arises from multiple interconnected barriers, including reduced intracellular drug accumulation, enhanced dr

OCT 18, 2026 · JOURNAL ARTICLE

Multifunctional Magneto‑Thermal Probe Enhances the Efficacy of Tumor Therapy as a Tumor Nanovaccine

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ABSTRACT Magnetic hyperthermia therapy (MHT) is an emerging thermotherapeutic approach that has shown promising potential in cancer treatment. However, conventional MHT strategies

OCT 16, 2026 · JOURNAL ARTICLE

Bismuth‐Triggered Copper Release From CuS Nanosheets Enables Synergistic Ion‐Interference and Chemodynamic/Photothermal Therapy

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Despite the promising potential of Cu-based nanozymes in cancer therapy, the therapeutic efficacy remains limited by the difficulty of achieving controlled Cu-ion release without c

OCT 15, 2026 · JOURNAL ARTICLE

A Nanodelivery Platform Harnessing Synthetic Lethality and Efferocytosis Inhibition for Synergistically Enhanced Immunotherapy of Triple‐Negative Breast Cancer

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ABSTRACT Triple‐negative breast cancer (TNBC), defined by the absence of specific therapeutic targets, shows poor clinical benefit and readily develops chemoresistance, underscorin

OCT 14, 2026 · JOURNAL ARTICLE

Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid

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ABSTRACT Lactate is a key biomarker of tissue metabolism and oxygenation, yet clinical assessment still relies on intermittent blood tests that overlook rapid metabolic dynamics an

OCT 14, 2026 · JOURNAL ARTICLE

Nanomotors: Preparation Strategies, Propulsion Mechanisms, and Applications in Cancer Therapeutics

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ABSTRACT Cancer remains one of the leading causes of human death globally. The capabilities of tumor cells for rapid proliferation, resistance to death, and metastasis have become

OCT 7, 2026 · JOURNAL ARTICLE

X‐Ray‐Responsive Engineered Bacteria for Synergistic Radioimmunotherapy and Photoacoustic Immunomonitoring of Triple‐Negative Breast Cancer

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ABSTRACT Engineered bacteria offer promising opportunities for cancer immunotherapy, yet precise in vivo activation and real‐time tracking of immune responses remain formidable cha

OCT 4, 2026 · JOURNAL ARTICLE

Engineering Nanoparticles to Navigate Biological Barriers for Deep Tumor Penetration

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Deep and spatially uniform drug delivery remains a major challenge in nanomedicine for solid tumor therapy. During delivery, nanoparticles must sequentially traverse multiple biolo