Scientific Reports

OCT 23, 2026 · JOURNAL ARTICLE

Distinct estrogenic transcription programs of estetrol and 17β-estradiol across mammary, uterine, and vaginal cell types of pseudomenopausal mice

Scientific Reports

Menopause results from a marked decline in estrogen production and leads to symptoms that impair quality of life. Menopausal hormone therapy effectively alleviates these symptoms b

OCT 23, 2026 · JOURNAL ARTICLE

Baseline adipokine profiles have limited predictive value for weight-loss outcomes after laparoscopic sleeve gastrectomy: a prospective longitudinal cohort study

Scientific Reports

Bariatric surgery is the most effective treatment for severe obesity, yet postoperative weight-loss outcomes vary considerably between individuals and reliable preoperative predict

OCT 22, 2026 · JOURNAL ARTICLE

Association of pre-existing cardiovascular disease with cardiovascular and clinical outcomes in patients receiving immune checkpoint inhibitors

Scientific Reports

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are increasingly associated with cardiovascular complications. The association between pre-existing cardiova

OCT 21, 2026 · JOURNAL ARTICLE

A tight inducible model for oncogene function and drug testing

Scientific Reports

Abstract Precise control of oncogene expression is crucial for advancing tumor biology research and therapeutic testing. To address the limitations of current systems, we developed

OCT 20, 2026 · JOURNAL ARTICLE

Anti-HER2 immunotoxin scFv-PE35KDEL internalizes via receptor-mediated endocytosis and induces apoptosis in ovarian cancer cells

Scientific Reports

Ovarian cancer remains a major cause of cancer-related mortality among women worldwide, highlighting the need for more effective targeted therapies. Immunotoxins have emerged as pr

OCT 20, 2026 · JOURNAL ARTICLE

Structure-based computational analysis of quercetin and withaferin A as prolactin receptor inhibitors for male breast cancer therapy

Scientific Reports

Abstract Male breast cancer (MBC) is a rare malignancy that is frequently diagnosed at advanced stages and managed using therapeutic strategies largely extrapolated from female bre

OCT 20, 2026 · JOURNAL ARTICLE

Quality, reliability, and content coverage of pleural effusion–related short videos on Douyin (TikTok) and Bilibili: a cross-sectional study

Scientific Reports

Pleural effusion is a common clinical finding with heterogeneous causes, including infection, malignancy, heart failure, tuberculosis, pulmonary embolism and systemic disease. Beca

OCT 20, 2026 · JOURNAL ARTICLE

Dietary inflammatory index in relation to metabolic health status, serum levels of brain-derived neurotrophic factor and adropin in Iranian adults

Scientific Reports

There was little evidence for the association of dietary inflammatory index (DII) and metabolic health status, and no evidence on DII and brain-derived neurotrophic factor (BDNF) a