SEP 2, 2026 · JOURNAL ARTICLE
Loss of function of ALDH3B2 transdifferentiates human pancreatic duct cells into β-like cells
Science Translational Medicine
A single-centre, mechanistic study identifying a gene target for β-cell transdifferentiation with proof-of-concept in primary human cells and mouse transplantation, but lacking human clinical data and requiring confirmation in larger systems.
Reported
Duration of glucose normalization…6 weeks