Renal Failure

AUG 26, 2026 · JOURNAL ARTICLE

Weight-adjusted waist index and risk of cardiovascular and all-cause mortality in chronic kidney disease: NHANES 2005-2018 analysis of 5,381 adults.

Renal Failure

Large prospective cohort study with hard clinical endpoints (CVD and all-cause mortality), robust adjusted effect sizes, and confirmation across subgroups and sensitivity analyses, but observational design precludes practice-changing status.

AUG 5, 2026 · JOURNAL ARTICLE

An explainable machine learning model for predicting in-hospital infection in patients with systemic lupus erythematosus.

Renal Failure

A machine learning model development study using retrospective electronic health records with internal validation but no external prospective validation, no clinical outcome trial, and no demonstration of impact on clinical decision-making or patient outcomes.

JUL 13, 2026 · JOURNAL ARTICLE

Impact of dual antiplatelet therapy duration after percutaneous coronary intervention on outcomes in acute coronary syndrome patients with and without chronic kidney disease: a nationwide cohort study.

Renal Failure

Observational cohort study with a large sample (4,800 patients) from a national database showing no benefit of prolonged DAPT on cardiovascular outcomes in ACS patients, but identifying a signal of increased bleeding in CKD subgroup; findings are exploratory and require confirmation.

JUL 9, 2026 · JOURNAL ARTICLE

Psychological resilience mediates the impact of anxiety and insomnia on health-related quality of life in maintenance dialysis patients.

Renal Failure

Cross-sectional study with multivariable regression and mediation analysis confirms known associations and quantifies mediating pathways in a well-defined clinical population.

JUN 23, 2026 · OBSERVATIONAL STUDY WITH TARGET TRIAL EMULATION

Amino acid infusion and acute kidney injury after aortic surgery: a multicenter observational study with target trial emulation.

Renal Failure

Observational study with target trial emulation found no significant association between amino acid therapy and AKI, though hypothesis-generating subgroup signal in older patients.

JUN 2, 2026 · JOURNAL ARTICLE

Clinical impact of an EHR-integrated hyperkalemia management system: a real-world study of 10,934 episodes.

Renal Failure

Large retrospective cohort comparing EHR-integrated system to routine care with improved process measures and reduced costs in select subgroups.

MAY 13, 2026 · JOURNAL ARTICLE

Comparative efficacy and safety of apixaban and rivaroxaban versus warfarin in atrial fibrillation patients with end-stage renal disease: a systematic review and meta-analysis.

Renal Failure

Meta-analysis of 3 RCTs and 8 observational studies shows apixaban and rivaroxaban associated with lower bleeding risk versus warfarin in dialysis patients with AF, but efficacy endpoints show substantial heterogeneity and RCT-only analysis lacked statistical significance; evidence is suggestive but requires dedicated large RCTs.

APR 7, 2026 · JOURNAL ARTICLE

Bibliometric analysis of sacubitril/valsartan in the management of chronic kidney disease (2013-2025).

Renal Failure

This is a bibliometric analysis of published literature, not a primary clinical study, and provides no original outcome data on sacubitril/valsartan efficacy or safety.