Pakistan Journal of Pharmaceutical Sciences

OCT 20, 2026 · JOURNAL ARTICLE

Isolation, identification and characterization of halophilic Salinicoccus roseus BMRL-13 and evaluation of its antimicrobial and thrombolytic potential

Pakistan Journal of Pharmaceutical Sciences

Background: Halophilic microorganisms thriving in high-saline environments are recognized as a significant source of novel bioactive metabolites. The rise in antimicrobial resistan

OCT 13, 2026 · JOURNAL ARTICLE

Impact of paclitaxel-, docetaxel- and trastuzumab-based treatment according to Ki-67 and E-cadherin expression in invasive ductal and lobular breast carcinoma

Pakistan Journal of Pharmaceutical Sciences

Abstract: Background: Breast cancer is still the most common cause of cancer death all over the world and invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) are i

OCT 12, 2026 · JOURNAL ARTICLE

Reserpine, a lipophilic indole alkaloid derived from Rauwolfia, targets ABCB1 to overcome docetaxel resistance in prostate cancer

Pakistan Journal of Pharmaceutical Sciences

Abstract: Background: Overexpression of ATP-binding cassette subfamily B member 1 (ABCB1) is a major driver of docetaxel resistance in prostate cancer. Thus, identifying effective

SEP 21, 2026 · JOURNAL ARTICLE

In-vitro study on the effect of cinnamaldehyde, eugenol and polydatin on the growth of Streptococcus mutans and the formation of dental plaque biofilms

Pakistan Journal of Pharmaceutical Sciences

Abstract: Background: Dental caries are chronic infectious diseases with a high global prevalence. Its pathogenesis is closely related to the adhesion of Streptococcus mutans (S. m

JOURNAL ARTICLE

Britanin improved high-fat diet-induced obesity by regulating the MAPK signaling pathway.

Pakistan Journal of Pharmaceutical Sciences

Single-center animal study with mechanistic validation but no human data, uncontrolled design, and surrogate endpoints only; insufficient for clinical guidance despite sound experimental approach.