Metabolites

SEP 3, 2026 · JOURNAL ARTICLE

Integrated Transcriptomics and Lipidomics Identify CES1-Mediated Maladaptive Lipolysis as a Key Target of Hyperlipidemic Acute Pancreatitis

Metabolites

Mechanistic discovery study combining transcriptomics, lipidomics, and a validated mouse model showing proof-of-mechanism for CES1 inhibition in hyperlipidemic acute pancreatitis, but limited to preclinical validation without human efficacy data.

AUG 18, 2026 · JOURNAL ARTICLE

Association Between Serum Magnesium Levels and Metabolic Dysfunction-Associated Steatotic Liver Disease in a Nationally Representative Sample of Korean Adults, 2024

Metabolites

A cross-sectional analysis in a large nationally representative sample showing an inverse association between serum magnesium and MASLD with statistical significance, but limited by observational design and inability to establish causation.

AUG 11, 2026 · JOURNAL ARTICLE

Biomarkers in Obesity-Related Metabolic Syndrome: Relationships Between LDL Subfractions, Lipid Profile, and Cardiometabolic Risk in a Slovak Population

Metabolites

Cross-sectional study in a single population identifying biomarker patterns and novel indices for cardiometabolic risk assessment in metabolic syndrome, with clear descriptive findings but limited by design and no intervention or outcome prediction validation.

AUG 11, 2026 · JOURNAL ARTICLE

Association of Waist Circumference and Body Composition Indices with Insulin Resistance in Prepubertal Children with Obesity

Metabolites

A sound cross-sectional study in a focused population identifying independent associations between body composition measures and insulin resistance using rigorous statistical adjustment, but limited by retrospective design, single-centre recruitment, and surrogate endpoint (HOMA-IR), requiring prospective validation.