The aim of this study was to evaluate the oncological justification for multivisceral pancreaticoduodenectomy with resection of the venous confluence (superior mesenteric and/or po
Abstract Purpose Trophoblast cell surface antigen 2 (TROP2) is a glycoprotein expressed on epithelial tumor cells and therefore an established target for antibody-drug conjugates (
Abstract Background The role of primary tumor resection (PTR) in patients with colorectal cancer (CRC) and unresectable distant metastases remains controversial. While PTR may prev
Abstract Background Metabolic and bariatric surgery (MBS) is an effective treatment for patients with obesity and type 2 diabetes (T2D). Preoperative T2D severity may influence per
The JCOG1109 trial proved the superiority of neoadjuvant chemotherapy (NAC) with docetaxel, cisplatin, and 5-fluorouracil (DCF) to chemotherapy with cisplatin and 5-fluorouracil (C
Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) have become an integral component of obesity management. Although these agents effectively induce preoperative w
Abstract Introduction The benefits of neoadjuvant therapy (NAT) for pancreatic cancer (PC) with portal venous involvement remain debated. This study aimed to compare the short- and
Single-Anastomosis Sleeve Jejunal Bypass (SASJ) is an innovative metabolic bariatric surgery (MBS) designed to achieve meaningful weight loss with minimal nutritional risks. As a m