Journal of Physiology and Biochemistry

NOV 3, 2026 · JOURNAL ARTICLE

Exposure to second-generation antipsychotics increases circulating small extracellular vesicles that promote insulin resistance in hepatocytes

Journal of Physiology and Biochemistry

Second generation antipsychotics (SGAs) are widely prescribed for the management of psychiatric disorders, yet their use is associated with obesity, insulin resistance, and impaire

SEP 28, 2026 · JOURNAL ARTICLE

Cold-induced serum amyloid A3 amplifies cAMP–PKA signaling to drive adaptive thermogenesis in brown adipocytes

Journal of Physiology and Biochemistry

The global rise in obesity and its associated comorbidities, including type 2 diabetes and cardiovascular disease, presents a major public health challenge. Adipose tissue plays a

SEP 26, 2026 · JOURNAL ARTICLE

Nucleotide metabolic reprogramming: a “double-edged sword” in obesity-related inflammation—from metabolic adaptation to pathological imbalance

Journal of Physiology and Biochemistry

Obesity has become a serious global public health challenge, characterized by chronic, sterile, low-grade inflammation with excessive NLRP3 inflammasome activation; however, the me

SEP 17, 2026 · JOURNAL ARTICLE

A combination of aerobic and resistance training induces white adipose tissue browning

Journal of Physiology and Biochemistry

Abstract Combined training (CT) has been widely recommended as a strategy to improve metabolic health and is often prescribed in the context of obesity and its comorbidities. The p