Although titanium dioxide (TiO 2 ) semiconductor nanomaterials have garnered considerable attention in radiotherapy research due to their photoelectric effect, the inefficient elec
Gastric cancer (GC), a leading global malignancy, urgently requires the discovery of novel diagnostic and therapeutic targets. The roles of extracellular vesicle (EV)- derived circ
Hypoxia within the tumor microenvironment severely compromises the therapeutic efficacy of photodynamic therapy (PDT) by limiting oxygen-dependent reactive oxygen species (ROS) gen
The complex and heterogeneous nature of cancer presents significant challenges to effective treatment. Because no single therapy can overcome this complex challenge, rational combi
Therapy-induced senescence (TIS) has emerged as an important contributor to treatment resistance and poor prognosis in clinical cancer therapy. Senescence initially acts as a tumor
Sepsis, a severe illness marked by immune dysregulation and widespread inflammation, involves macrophage pyroptosis as a key player. This study explores the impact of RNA N6-methyl
Abstract PD-1/PD-L1 blockade benefits patients across > 20 cancer types, yet durable responses remain limited and antibody therapies only transiently engage the axis while causing
Acquired cisplatin resistance remains a major challenge in cancer therapy and is frequently associated with enhanced RAD51-mediated homologous recombination (HR) repair. Here, we i