Journal of High School Science

OCT 21, 2026 · JOURNAL ARTICLE

Evolution-informed rescue drug design: exploiting acquired resistance to develop more selective and resistance-durable targeted therapies

Journal of High School Science

Acquired resistance to targeted anticancer drugs presents an evolutionary paradox: mutations that allow cancer cells to escape an initial inhibitor may simultaneously create molecu

JUL 24, 2026 · JOURNAL ARTICLE

Temporal Connectomics for actigraphy-based psychiatric stratification: a comparative study of circadian, entropy, graph, and sequence representations

Journal of High School Science

A single-centre, cross-validated algorithmic study on a public dataset using surrogate endpoints (classification performance) without external validation, clinical outcomes, or comparison to clinical diagnosis.