Skin cancer therapy continues to face challenges in achieving selective tumour targeting while limiting damage to healthy tissue. Gold nanoparticles (AuNPs) and silver nanoparticle
:Premature drug release in the systemic circulation or at off-target sites remains a major challenge in conventional drug delivery systems, often resulting in reduced therapeutic e
Early-stage preclinical study in an animal model demonstrating formulation optimization and proof-of-concept for a nanocarrier delivery strategy; lacks human efficacy data and clinical outcomes.
This is a narrative review article synthesizing preclinical and early translational work on carrier-free nanoparticles; it raises questions and organizes the field rather than reporting original clinical trial data or definitive evidence.