Source

JCO Oncology Practice

2 developments in the corpus

Latest

Everything in the corpus, newest first.

SEP 4, 2026 · JOURNAL ARTICLE

Characterizing Time Toxicity in Lung Cancer Clinical Trials: Development and Application of a Novel Time Burden Metric

JCO Oncology Practice

Descriptive analysis of protocol-derived metrics across historical trials with no patient-level validation, establishing feasibility of a novel measurement framework rather than testing clinical impact.

PreliminaryLyudmila Bazhenova Lisa Madlensky Sonia Jain

Reported

Median time toxicity (2005–2014)63.8

IQR time toxicity (2005–2014)41.8–109.3

Median time toxicity (2015–2024)82

AUG 19, 2026 · JOURNAL ARTICLE

Translating CRISPR to Practice in the Clinic: Transformative Therapy in Hemoglobinopathies and Emerging Applications in Malignancies

JCO Oncology Practice

Expert consensus and implementation guidance on clinical translation of CRISPR-based therapy in hemoglobinopathies with established regulatory approval, addressing delivery, patient selection, and barriers to practice integration.

Expert GuidanceRabi Hanna Miza Salim Hammoud Hemoglobinopathies and Related Disorders

Study details

InterventionExagamglogene autotemcel: ex vivo CRISPR-Ca…