The development of single-dose vaccines capable of inducing durable humoral and cellular immune responses would eliminate the need for additional booster doses, which is particular
Osteoarthritis is a whole-joint disease characterized by persistent inflammation, immune dysregulation, oxidative stress, cellular senescence, and impaired cartilage repair. Curren
A comprehensive review synthesizing current knowledge on biomaterial-based drug delivery for head and neck cancer, identifying clinical challenges and therapeutic opportunities without presenting original experimental data or clinical trial results.
This is a narrative review proposing conceptual frameworks for nanoparticle-mediated CRISPR delivery; it does not report primary experimental data, efficacy outcomes, or comparative evidence.
This is a systematic review article synthesizing mechanisms, delivery methods, challenges, and safety considerations for mRNA-LNP therapeutics in pulmonary disorders, providing expert assessment of the field rather than reporting original trial data.
Preclinical proof-of-concept in cell and animal models showing a novel nanoparticle formulation induces ferroptosis and tumor inhibition, but lacks human efficacy data, safety characterization, and direct comparator controls.
This is a narrative review synthesizing preclinical and emerging evidence on copper-based nanoplatforms; no original experimental data, clinical trials, or comparative efficacy data are presented.