International Journal of Nanomedicine

OCT 31, 2026 · JOURNAL ARTICLE

Metal–Organic Framework–Based Nanomedicines for Cancer Therapy: A Proposed Delivery Framework for Executable Cuproptosis

International Journal of Nanomedicine

Abstract: Metal–organic frameworks (MOFs) can coordinate copper, catalytic sites and therapeutic cargo within one carrier, offering opportunities to control copper exposure and cel

OCT 31, 2026 · JOURNAL ARTICLE

NIR-Responsive Mitochondria-Targeted Liposomal Covalent Organic Framework for Combined Cancer Therapy

International Journal of Nanomedicine

Background: Nanoplatform-based combination therapy offers a promising route for enhanced cancer therapy. Despite the advance of nanomedicine, the precise subcellular co-delivery an

OCT 1, 2026 · JOURNAL ARTICLE

Nanocarrier-Integrated Topical Dosage Forms for Biofilm-Infected Wounds: Balancing Wound Retention, Biofilm Matrix Penetration, and Translational Feasibility

International Journal of Nanomedicine

Abstract: Biofilm-infected wounds are difficult to treat because extracellular polymeric substance (EPS) matrices, wound exudate, polymicrobial spatial organization, impaired antim

OCT 1, 2026 · JOURNAL ARTICLE

Potential Therapeutic Applications of Spherical Nucleic Acids (SNAs) in Cancer: Key Observations and Insights

International Journal of Nanomedicine

Abstract: Spherical nucleic acids (SNAs) are a unique class of nucleic acid nanotherapeutics characterized by densely packed, radially arranged oligonucleotides surrounding a nanop

OCT 1, 2026 · JOURNAL ARTICLE

Organelle-Targeted Nanocarriers for Cancer Therapy: Design Principles, Intracellular Trafficking, and Translational Barriers in Precision Drug Delivery

International Journal of Nanomedicine

Abstract: The clinical translation of cancer nanomedicine remains constrained by inefficient intracellular delivery, poor subcellular specificity, and limited tumor accumulation, h

OCT 1, 2026 · JOURNAL ARTICLE

Dimensionally Engineered Nanotherapeutics for Pulpitis and Periodontitis: From Structural Design to Artificial Intelligence-Enabled Precision Therapy

International Journal of Nanomedicine

Abstract: Pulpitis (Pul) and periodontitis (PD) are oral infectious diseases with extremely high global prevalence. These pathologies can induce severe pain, significantly elevate

SEP 30, 2026 · JOURNAL ARTICLE

Polymeric Nanomedicines for siRNA Delivery in Hepatocellular Carcinoma: Emerging Therapeutic Strategies, Combination Approaches, and Translational Perspectives

International Journal of Nanomedicine

Abstract: Hepatocellular carcinoma is the sixth most common cancer worldwide and a leading cause of cancer related mortality. Risk factors include chronic hepatitis B/C, obesity, a

SEP 1, 2026 · JOURNAL ARTICLE

Nanotechnology-Enhanced Delivery and Bioactivity of Dietary Flavonoids: Overcoming Bioavailability Barriers for Targeted Antimicrobial and Antiviral Therapies-A Comprehensive Review

International Journal of Nanomedicine

This is a narrative review synthesizing preclinical evidence on nanotechnology-enhanced flavonoid delivery; it raises mechanistic and translational questions rather than reporting original clinical or rigorous experimental data to answer them.