Abstract Background Health-related quality of life (HRQoL) often deteriorates during later-line treatment for advanced gastric cancer. Although nivolumab monotherapy has been an es
Abstract Background Chemotherapy-induced neutropenia (CIN) has been considered a favorable prognostic marker across multiple cytotoxic regimens for gastrointestinal malignancies. H
Abstract Background Locomotive syndrome (LS) is a clinical condition used to describe reduced mobility caused by musculoskeletal dysfunction and is highly prevalent among patients
Abstract Background Immune checkpoint inhibitors (ICIs) are a standard treatment for advanced non-small cell lung cancer (NSCLC), but clinically practical predictors of immune-rela
Abstract Background Cancer of unknown primary (CUP) remains a challenging malignancy with a poor prognosis. Although immune checkpoint inhibitors have shown activity in CUP, availa
Rigorous phase 3 pooled analysis demonstrating a clinically meaningful OS benefit (HR 0.46) with durable 5-year survival gains in a population with high unmet need and poor prognosis, though sample size in the Japanese subgroup is modest.