Invasive Streptococcus pyogenes (group A streptococcus, GAS) infection is associated with substantial morbidity and mortality and has shown a notable resurgence in several countrie
Background. Paediatric ventilator-associated pneumonia (VAP) worsens outcomes and mortality. Characterizing local microbiology and resistance patterns is crucial for empirical ther
A well-designed quasi-experimental study with prospective audit showing statistically significant improvements in prescription appropriateness and meaningful reductions in broad-spectrum antibiotic use, but limited by single-centre design and surrogate endpoints rather than hard clinical outcomes.
Background. Multi-drug-resistant (MDR) Escherichia coli display a growing infection-control concern in hospitals, yet the duration of faecal carriage and risk factors for persisten
Legionella species are environmental Gram-negative bacteria capable of colonising artificial water systems and causing Legionnaires' disease, a severe form of atypical pneumonia. H
A well-designed retrospective matched case–control study from six tertiary hospitals with clear findings on SSI timing and risk factors, but limited by retrospective design, modest case numbers, and single-country setting that requires confirmation.
Introduction. Multi-drug-resistant Gram-negative bacteria (MDR-GNB) are a major healthcare challenge, particularly among patients admitted to intensive care units (ICUs). The objec
Single-centre retrospective cohort showing IDST intervention independently associated with reduced 28- and 90-day mortality in MRSA bacteraemia, with hazard ratios 0.328 and 0.427 respectively, but limited by retrospective design, small sample, and single-site conduct.