OCT 23, 2026 · JOURNAL ARTICLE
Complete loss of all mismatch repair protein expression in endometrioid carcinoma: A first case report of null phenotype induced by MLH1 hypermethylation and MSH2 somatic mutation
Gynecologic Oncology Reports
Background Endometrial cancer (EC) is a heterogeneous disease comprising four molecular subtypes, one of which is mismatch repair-deficient (MMRd). Immunohistochemical (IHC) evalua