Gut

NOV 4, 2026 · JOURNAL ARTICLE

Tissue-regulatory T cells influence anti-cancer and pro-repair functions in the exocrine pancreas

Gut

Background Regulatory T cells (Tregs) are fundamentally important for maintaining immune homeostasis, and their potent immune-suppressive roles make them attractive immunotherapeut

OCT 12, 2026 · JOURNAL ARTICLE

Boosting the nuclear Wnt/β-catenin feedback loop for the specific elimination of colorectal cancer

Gut

Background The hyperactivation of the Wnt/β-catenin pathway, which is driven primarily by Adenomatous polyposis coli (APC) mutations, is a hallmark and driver of colorectal cancer

SEP 30, 2026 · JOURNAL ARTICLE

Rewinding the gut clock: from chronodisruption to targeted therapies

Gut

Circadian rhythms orchestrate daily oscillations in physiology and behaviour, enabling optimal alignment between internal biological processes and environmental cycles. A hierarchi

SEP 24, 2026 · JOURNAL ARTICLE

Expert consensus on clinical trials for use of systemic therapy in patients with hepatocellular carcinoma undergoing surgical and locoregional therapies

Gut

Background Advances in systemic therapy for advanced hepatocellular carcinoma (HCC) have fuelled a growing interest in evaluating these therapies in earlier stages of disease. Howe

SEP 21, 2026 · JOURNAL ARTICLE

Prior endoscopic surveillance and diagnosis of Barrett-related dysplasia and cancer: evidence from a nationwide Dutch cohort

Gut

Background In patients with Barrett oesophagus (BE), surveillance aims to detect dysplasia or oesophageal adenocarcinoma (EAC) early. Whether most asymptomatic patients undergoing

SEP 16, 2026 · JOURNAL ARTICLE

Longitudinal gut microbiome dynamics during immunotherapy identify microbial features of clinical benefit in advanced primary liver cancer

Gut

Background The gut microbiome has been linked to immune checkpoint inhibitor (ICI) outcomes, but the temporal dynamics of microbial communities during treatment remain poorly chara