Frontiers in Molecular Biosciences

OCT 20, 2026 · JOURNAL ARTICLE

Research progress on the key cuproptosis regulator FDX1 and its relevance to triple-negative breast cancer

Frontiers in Molecular Biosciences

Cuproptosis, a recently identified form of programmed cell death driven by copper ion overload, occurs in a manner highly dependent on mitochondrial respiration and is orchestrated

OCT 16, 2026 · JOURNAL ARTICLE

Do fungal pathogens exploit HLA-G-mediated immune tolerance?

Frontiers in Molecular Biosciences

Fungal pathogens employ diverse strategies to evade host immunity and establish persistent infection, yet the contribution of immune checkpoint pathways to fungal pathogenesis rema

OCT 15, 2026 · JOURNAL ARTICLE

Peroxiredoxins in disease biology: molecular mechanisms and therapeutic opportunities

Frontiers in Molecular Biosciences

Peroxiredoxins (PRDXs) are thiol-specific antioxidant enzymes that maintain cellular redox balance and regulate signaling pathways. They participate in the development of cancer, n

OCT 13, 2026 · JOURNAL ARTICLE

The amino acid transporters SLC38A3–SLC38A5–SLC38A7 as novel anti-cancer therapeutic targets

Frontiers in Molecular Biosciences

System N amino acid transporters SLC38A3 and SLC38A5 are carriers capable of mediating net inward or outward fluxes of substrates, such as glutamine, asparagine and histidine, coup

OCT 13, 2026 · JOURNAL ARTICLE

Spatial lipidomics in gynecologic malignancies: molecular identification, cellular attribution, and mechanistic validation

Frontiers in Molecular Biosciences

Spatial lipidomics can place lipid identities within histopathologic compartments, but ion maps are frequently interpreted beyond what their analytical and biological validation ca

OCT 1, 2026 · JOURNAL ARTICLE

Exosomal microRNAs as biomarkers of multimorbidity risk in lean and obese women with polycystic ovary syndrome

Frontiers in Molecular Biosciences

Polycystic ovarian syndrome (PCOS) is a multifactorial endocrine disorder that is characterised by reproductive, metabolic and cardiometabolic abnormalities. Besides typical hormon

SEP 23, 2026 · JOURNAL ARTICLE

Therapeutic reprogramming of natural killer cells for solid tumors: expanding frontiers into rare and ultra-rare malignancies

Frontiers in Molecular Biosciences

Rare and ultra-rare solid tumors collectively account for approximately one-quarter of all cancer diagnoses yet remain associated with poor clinical outcomes. Delayed diagnosis, li

SEP 23, 2026 · JOURNAL ARTICLE

The impact of zeaxanthin and lycopene on fatty acid beta-oxidation in isolated peroxisomes from frozen livers of obese rats

Frontiers in Molecular Biosciences

Over the past decade, research has emphasized the role of organelle dysfunction in various diseases, particularly obesity and related metabolic disorders. Peroxisomes, essential fo