Frontiers in Genetics

OCT 22, 2026 · JOURNAL ARTICLE

Early enteral nutrition and perioperative peripheral immune-cell dynamics after gastrectomy for gastric cancer

Frontiers in Genetics

Background Immune checkpoint inhibitors (ICIs) have changed advanced gastric cancer (GC) treatment, but response remains heterogeneous. Radical gastrectomy causes transient periope

OCT 21, 2026 · JOURNAL ARTICLE

Treg and immune proliferative programs characterize anti-PD-1-responsive endometrial cancer: an integrative single-cell, spatial transcriptomic, and TCGA-UCEC reanalysis

Frontiers in Genetics

Background The responses to programmed cell death protein 1 (PD-1)-based therapy in advanced endometrial cancer are heterogeneous. The cellular programs associated with such respon

OCT 20, 2026 · JOURNAL ARTICLE

Artificial intelligence assisted genomic profiling of ovarian cancer liver metastases

Frontiers in Genetics

Liver involvement in ovarian cancer is often treated as a single clinical entity, although liver-surface implants and parenchymal deposits occupy different anatomical settings and

OCT 9, 2026 · JOURNAL ARTICLE

Saliva-based genomic signatures for early detection of oral squamous cell carcinoma: the state and perspectives of translation

Frontiers in Genetics

Oral squamous cell carcinoma (OSCC) is one of the leading causes of cancer morbidity and mortality globally, and prognosis is closely related to the stage at diagnosis. Although ad

SEP 24, 2026 · JOURNAL ARTICLE

Artificial intelligence for precision gene therapy: emerging technologies, clinical applications, and future directions

Frontiers in Genetics

Artificial Intelligence (AI) is revolutionizing gene therapy from an empirical and iterative process to a predictive, data-driven and increasingly intelligent therapeutic developme

SEP 17, 2026 · JOURNAL ARTICLE

Beyond local control: radiotherapy–immunotherapy combinations from in situ vaccination to systemic immune remodeling

Frontiers in Genetics

Background Radiotherapy (RT) is evolving from local cytotoxicity to systemic immunomodulation. Acting as an in situ vaccine, RT initiates antitumor immunity via immunogenic cell de

SEP 17, 2026 · JOURNAL ARTICLE

Off-target drug repurposing for rare and ultra-rare cancers: towards a scalable therapeutic framework

Frontiers in Genetics

Drug repurposing represents a pragmatic strategy for patients with cancer who have limited standard-of-care options. Traditional in silico or functional repurposing approaches ofte

AUG 6, 2026 · JOURNAL ARTICLE

Genetic associations and candidate functional genes linking depression and obesity: a multi-omics integrative study

Frontiers in Genetics

This is an exploratory multi-omics study generating mechanistic hypotheses about shared genetic pathways in depression and obesity, with inconclusive bidirectional evidence and candidate genes requiring experimental validation.