Frontiers in Bioengineering and Biotechnology

OCT 12, 2026 · JOURNAL ARTICLE

Low-affinity anti-HER2-CAR T cells efficiently eradicate HER2+ and HER2low cancer cells with reduced toxicity on healthy tissue

Frontiers in Bioengineering and Biotechnology

Chimeric antigen receptor (CAR) T cell therapy is considered a therapeutic breakthrough in hematological malignancies. However, its translation to metastasized solid tumors remains

SEP 24, 2026 · JOURNAL ARTICLE

A Trojan horse nanoplatform overcoming delivery barriers for targeted gene immunotherapy of colorectal cancer

Frontiers in Bioengineering and Biotechnology

Programmed cell death ligand 1 (PD-L1) antibody has been shown to hold tremendous promise in curing metastatic colorectal cancer (CRC). However, the delivery efficacy of the target

SEP 23, 2026 · JOURNAL ARTICLE

Medical device biomaterials and antimicrobial resistance: exploring an overlooked research interface

Frontiers in Bioengineering and Biotechnology

Modern healthcare depends heavily on polymer-based medical devices (1). Among these, polyvinyl chloride (PVC) is widely used in has become the predominant material used in a wide r

SEP 14, 2026 · JOURNAL ARTICLE

Hollow-degree-tuned Prussian blue–mesoporous silica nanoplatforms for chemo-photothermal cancer therapy with preliminary microfluidic perfusion evaluation

Frontiers in Bioengineering and Biotechnology

Background Balancing photothermal performance and drug-delivery capacity remains a key challenge in the structural design of multifunctional nanomedicines. Hollowing can increase i

AUG 24, 2026 · JOURNAL ARTICLE

Gene therapy for genodermatoses at the crossroads of innovation and clinical translation

Frontiers in Bioengineering and Biotechnology

A comprehensive review synthesizing current state, clinical milestones, and translational barriers in gene therapy for genodermatoses, offering expert perspective on therapeutic landscape and implementation challenges.

AUG 17, 2026 · JOURNAL ARTICLE

Engineered MSC-exosomes as CRISPR-Cas9 delivery vectors for precision immunotherapy

Frontiers in Bioengineering and Biotechnology

This is a narrative review synthesizing mechanistic understanding and engineering strategies rather than reporting original experimental data or clinical outcomes, making it exploratory rather than evidence of efficacy.