Background Online news media increasingly shapes patient understanding of musculoskeletal disease and influences care-seeking behavior. Foot and ankle (F&A) conditions are managed
Retrospective cohort study with propensity matching in a large registry showing differential effects of GLP-1 use on ankle OA interventions by metabolic phenotype, but limited by observational design, inability to control unmeasured confounding, and lack of mechanistic explanation for conflicting outcomes between cohorts.