AUG 7, 2026 · JOURNAL ARTICLE
RPLP0 drives diffuse large B‑cell lymphoma cell proliferation through reactive oxygen species‑dependent AKT/mTOR activation and inhibition of stress‑induced autophagy
Experimental and Therapeutic Medicine
Mechanistic study in cell lines demonstrating a signaling pathway without clinical outcome data, efficacy comparison, or in vivo validation; raises questions about RPLP0's therapeutic potential rather than answering them.
Study details
DesignIn vitro mechanistic study with gene expres…
InterventionRPLP0 overexpression or knockdown; pharmaco…
ComparatorControl cells with baseline RPLP0 expressio…