SEP 12, 2026 · JOURNAL ARTICLE
Discovery of a brain penetrant NLRP3 inflammasome inhibitor that reduces neuropathic pain in mice.
European Journal of Medicinal Chemistry
In our continuing campaign to discover novel inhibitors of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) protein 3 (NLRP3), an emerging drug target that t