OCT 1, 2026 · JOURNAL ARTICLE
Proprotein Convertase Subtilisin/Kexin Type 9: From Biology to Therapeutic Targeting in Cardiovascular Disease
European Journal of Clinical Investigation
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a pivotal regulator of cholesterol homeostasis, primarily known for inducing the degradation of the low-density