Cumhuriyet Science Journal

OCT 27, 2026 · JOURNAL ARTICLE

LY2109761 Potentiates 5-FU-Induced Cytotoxicity in HCT 116 Cells and Preserves PBMC Viability In Co-Culture Models

Cumhuriyet Science Journal

Colorectal cancer remains a leading cause of cancer-related mortality worldwide, with chemoresistance representing a major therapeutic challenge. The transforming growth factor-bet

OCT 27, 2026 · JOURNAL ARTICLE

Dose-Dependent Downregulation of miR-335-5p in Response to Tamoxifen Reveals a PIAS4–ESR1 Regulatory Axis in Breast Cancer Cells

Cumhuriyet Science Journal

Breast cancer remains the most frequently diagnosed cancer among women worldwide, and estrogen receptor–positive (ER+) tumors are primarily treated with endocrine therapies; howeve

OCT 27, 2026 · JOURNAL ARTICLE

Combined Anticancer Effects of Curcumin and Serotonin on U87 Human Glioblastoma Cells: In Vitro and Molecular Docking Analysis

Cumhuriyet Science Journal

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor and is characterized by rapid proliferation, extensive invasion, and resistance to conventional therapies.