Communications Medicine

AUG 14, 2026 · JOURNAL ARTICLE

Data-driven phenotypic clustering of sleep-disordered breathing and long-term cardiovascular risk

Communications Medicine

Rigorous prospective cohort study with adjudicated hard cardiovascular endpoints, clear phenotype-based risk stratification with internal and external validation, showing clinically meaningful hazard ratios that outperform standard AHI scoring.

AUG 4, 2026 · JOURNAL ARTICLE

Polygenic risk-informed white matter integrity improves deep learning-based prediction of youth depression

Communications Medicine

A deep learning model combining polygenic risk scores and neuroimaging achieves moderate discrimination (AUC 0.61–0.67) for predicting youth depression cross-sectionally and at 2-year follow-up, with cross-ethnic validation, but lacks comparison to clinical gold standards and requires external prospective validation.