Lipid nanoparticles (LNPs) have emerged as the most clinically validated nanocarrier platform in oncology, transitioning from liposomal chemotherapy to the cornerstone of mRNA-base
Despite the recent progress in cancer treatment, the 5-year survival rates for many types of cancer are still below 30%. The current therapeutic modalities are subject to significa
Breast cancer is the most common malignancy worldwide. Patients with advanced disease often experience recurrence and metastasis, driven by the immunosuppressive tumor microenviron
Stem cells, known for their exceptional self-renewal and multilineage differentiation capabilities, play critical roles in tumor initiation, progression, and therapeutic strategies
Natural active compounds (NACs) possess diverse anticancer activities but are often limited by poor aqueous solubility, low bioavailability, insufficient tumor selectivity, and ina
Triple-negative breast cancer (TNBC) remains one of the most aggressive breast cancer subtypes, with high metastatic potential, frequent recurrence, and limited treatment options d
This is a narrative review of piezoelectric nanozyme mechanisms and design strategies in preclinical cancer models, raising conceptual and mechanistic questions rather than reporting clinical outcomes or rigorous comparative efficacy data.