Despite advances in multimodal therapy, effective treatments for aggressive oral squamous cell carcinoma (OSCC) remain limited, underscoring the need for actionable therapeutic tar
Abstract Background Cancer-associated fibroblasts (CAFs) are instrumental in tumor progression by interacting with tumor cells, other stromal components, and the extracellular matr
Muscle-invasive bladder cancer is most often treated with radical surgery and perioperative cisplatin-based chemotherapy, this represents a challenge for patient survival due to ci
Abstract Plasma treated solutions (PTS) have emerged as a promising anticancer strategy due to their ability to generate reactive oxygen and nitrogen species (RONS) that induce oxi
Gastric cancer (GC) is a highly aggressive malignancy with poor prognosis, characterized by complex tumor microenvironment (TME) interactions. Migrasomes have been implicated in ca
Abstract Introduction The development of new organ-preserving treatment alternatives is still an important issue in bladder cancer (BCa) research. A combination of minimally-invasi
Mechanistic in vitro study in cell lines with RNA sequencing showing ECT2's role in PTC proliferation and drug resistance; lacks in vivo validation, clinical trial data, or prospective patient outcomes.
This systematic review of preclinical animal models raises mechanistic questions about PDT's potential to trigger systemic immunity but does not provide clinical evidence sufficient to guide practice or confirm efficacy in humans.