Biomolecules

SEP 8, 2026 · JOURNAL ARTICLE

Bufalin-Loaded Multifunctional Nanodrugs for Cancer Therapy: Mechanisms, Delivery Strategies, and Translational Perspectives

Biomolecules

This is a narrative review synthesizing preclinical mechanistic evidence and nanocarrier design strategies for bufalin, with no clinical trials, efficacy data, or comparative outcomes reported.

SEP 4, 2026 · JOURNAL ARTICLE

Thymoquinone Is Effective in Painful Paclitaxel-Induced Peripheral Neuropathy Without Compromising Anticancer Activity

Biomolecules

Early-stage preclinical and animal study demonstrating analgesic efficacy of thymoquinone in paclitaxel-induced neuropathy, but with limited structural neuroprotection and no human data, requiring confirmation before clinical translation.

AUG 18, 2026 · JOURNAL ARTICLE

Shared Major Metabolic Pathways and Potential Targeted Therapies in Malignancies and Systemic Lupus Erythematosus

Biomolecules

A narrative review synthesizing mechanistic observations about shared metabolic pathways in cancer and SLE, proposing therapeutic hypotheses rather than reporting new empirical evidence or clinical outcomes.

AUG 8, 2026 · JOURNAL ARTICLE

Enolase-1 and Inflammation

Biomolecules

This is a narrative review synthesizing mechanistic evidence and existing literature on ENO-1's role in inflammation, raising questions about compartment-specific therapeutic targeting rather than reporting new empirical evidence.

AUG 8, 2026 · JOURNAL ARTICLE

Mechanisms of Obesity-Related Kidney Disease: From Adipose Depot Biology to the Chymase–Aldosterone and Ghrelin–Leptin Axes

Biomolecules

A comprehensive mechanistic review synthesizing evidence on obesity-driven kidney injury pathways and proposing candidate mechanisms and emerging therapies, but presenting no primary data, clinical trial results, or effect sizes to support claims.

AUG 7, 2026 · JOURNAL ARTICLE

Senescence-Related SOCS1, SOCS2, and GADD45G Identify an Immune-Associated Molecular Signature in Metabolic Dysfunction-Associated Steatotic Liver Disease

Biomolecules

Integrative transcriptomic and experimental study identifying a three-gene signature in MASLD with in vitro validation and murine model support, but lacking human clinical outcome data or mechanistic proof of causation.