Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder that results in severely elevated low-density lipoprotein cholesterol (LDL-C) due to dysfunctional activi
Inference regarding the longitudinal association between diet and coronary artery calcification (CAC) progression is limited, particularly when using empirically derived dietary pa
Diet and nutrition remain significant but modifiable drivers of cardiometabolic diseases (CMDs), yet the contemporary burden and future impact of diet-attributable CMDs in the Unit
Up to three-quarters of primary hypertension is epidemiologically attributed to excess adiposity. Incretin-based therapies are consistently associated with reduced blood pressure (
While proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as an effective therapeutic target in secondary prevention of cardiovascular disease (CVD), its role in prim
The PRagmatic study Of Messaging to Providers about Treatment of HyperLIPIDemia (PROMPT-LIPID) single-system pragmatic, randomized trial demonstrated that an electronic health reco
Airborne particulate matter (PM) increases the risk of cardiovascular disease. High efficiency particulate arrestance (HEPA) filtration can reduce indoor PM, but evidence is lackin
The smallest worthwhile difference (SWD) - the minimum absolute benefit required to justify a treatment against its burdens - varies by personal preference. We investigated factors