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American Journal of Physiology-heart and Circulatory Physiology

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SEP 8, 2026 · JOURNAL ARTICLE

Sex-Dependent Epigenomic and Transcriptomic Reprogramming Links Maternal Obesity to Cardiac Remodeling in Adult Offspring

American Journal of Physiology-heart and Circulatory Physiology

Mechanistic mouse model study identifying epigenetic and transcriptomic associations with maternal obesity and cardiac remodeling, but without functional validation or human translation to support clinical application.

Hypothesis-GeneratingTim D. Wilson Cameron Broberg Elysse A. Phillips

Reported

Study population modelMouse offspring of high-fat diet–fed mother…

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