Objectives: With improvements in systemic therapy for pancreatic cancer (PC), the role of radiation therapy (RT) to optimize local control has increased. While the tolerability and
Objectives: Sacituzumab govitecan (SG), a Trop-2–directed antibody-drug conjugate delivering SN-38, has shown promising activity in advanced breast cancer. However, variability acr
Meta-analysis of single-arm cohorts showing encouraging efficacy (ORR 53.9%) and manageable safety, but limited by lack of randomized comparator and reliance on surrogate endpoints; requires confirmatory RCT evidence.
Single-center retrospective study without a control arm comparing GLP-1 RA users to non-users; observational design with potential confounding limits causal inference about GLP-1 RA's specific role in GI adverse events during platinum chemotherapy.