Advanced Science

AUG 18, 2026 · JOURNAL ARTICLE

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science

First-in-class preclinical work demonstrating a novel nanoparticle approach in animal xenograft models; lacks human efficacy data, controlled comparators, and peer-reviewed publication details required for clinical translation.

AUG 17, 2026 · JOURNAL ARTICLE

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

Advanced Science

Mechanistic study identifying F7 as a driver of gastric cancer metastasis through cell signaling and microenvironment remodeling, with a potential therapeutic compound tested in model systems but no clinical efficacy data reported.

AUG 17, 2026 · JOURNAL ARTICLE

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science

Mechanistic study proposing a dual-role model of tamoxifen in shaping the tumor microenvironment and suggesting a combination strategy; lacks clinical efficacy data and appears exploratory in nature.

AUG 11, 2026 · JOURNAL ARTICLE

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science

Early-stage preclinical work in animal models demonstrating a novel nanoparticle platform with mechanistic activity; lacks human data, direct clinical comparators, and independent replication required for clinical translation claims.

AUG 11, 2026 · JOURNAL ARTICLE

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science

This is a mechanistic chemistry and cell biology study demonstrating a novel compound's effects on metabolic pathways and immune cells in vitro/in vivo, without clinical efficacy data or human translation.

AUG 11, 2026 · JOURNAL ARTICLE

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science

Mechanistic study in cell and animal models identifying a pathway by which AR-driven copper buffering might be exploited; lacks clinical trial data or human outcome evidence.

AUG 10, 2026 · JOURNAL ARTICLE

PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR‐T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy

Advanced Science

Preclinical mechanistic study in immunocompetent mice with engineered CAR-T cells, informing an ongoing Phase 1 trial; no human efficacy or safety data reported.

AUG 10, 2026 · JOURNAL ARTICLE

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science

Mechanistic discovery of a natural product's antibacterial action in vitro and structural characterization, without clinical efficacy or safety data in humans.