Advanced Functional Materials

OCT 15, 2026 · JOURNAL ARTICLE

Photodynamic Therapy‐Primed and Enzyme Cascade‐Fueled in Situ Prodrug Self‐Assemblies for Self‐Amplifying Chemotherapy

Advanced Functional Materials

ABSTRACT Tumor heterogeneity remains a major translational challenge for targeted therapies, particularly those employing multi‐targeted precision strategies. To overcome this barr

OCT 11, 2026 · JOURNAL ARTICLE

Finishing Touch via Metal Coordination: A Photoactivatable Organic Semiconducting Prodrug for Triply Synergistic Amplified Cancer Phototheranostics

Advanced Functional Materials

ABSTRACT Photothermal therapy (PTT), photodynamic therapy (PDT), and NIR‑II fluorescence imaging are each compromised by tumor hypoxia, thermotolerance, and insufficient contrast,

SEP 28, 2026 · JOURNAL ARTICLE

A Dragon‐Fruit‐Like Nanoplatform Containing Polydopamine‐Wrapped Selenium Quantum Dots Boosts Synergistic Chemo‐Photothermal Therapy for Triple‐Negative Breast Cancer

Advanced Functional Materials

ABSTRACT Triple‐negative breast cancer (TNBC) remains a significant clinical challenge due to lack of targetable biomarkers and systemic toxicity of conventional chemotherapy. To a

SEP 21, 2026 · JOURNAL ARTICLE

Heteroatom Acceptor Engineering Boosts NIR‑II Phototheranostics of Quinoid–Donor–Acceptor Semiconducting Polymers

Advanced Functional Materials

ABSTRACT Multimodal phototheranostics utilizing a single, integrated molecular platform represents a streamlined and efficient strategy for precise cancer therapy. Herein, we first

SEP 12, 2026 · JOURNAL ARTICLE

AI‐Enabled Organoid Chips for Modeling and Decoding Nerve‐Tumor Interactions

Advanced Functional Materials

ABSTRACT The nervous system is emerging as a central regulator of tumor initiation, progression, and therapeutic response. However, the dynamic mechanisms linking neural activity t

SEP 4, 2026 · JOURNAL ARTICLE

A Fluorescence‐Free Electronic Resonance Raman Probe for Surgical Navigation and Postsurgical Photothermal Immunotherapy of Local Tumors and Distal Metastases

Advanced Functional Materials

This is an early-stage preclinical study demonstrating proof-of-concept for a novel theranostic nanoparticle in mouse models of TNBC, with no human data, no clinical outcomes, and no comparison to standard surgical or immunotherapeutic approaches.

AUG 10, 2026 · JOURNAL ARTICLE

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials

First-in-vivo proof-of-concept of a novel implantable drug delivery platform in xenograft model; demonstrates feasibility but lacks comparative control arm, detailed efficacy metrics, and systemic biodistribution data needed for clinical translation.