SEP 4, 2026 · JOURNAL ARTICLE
Adverse childhood experiences and chronic liver diseases: Dose-response, type-specific associations, and mediation analyses
Acta Psychologica
Large prospective cohort study with 107,363 participants, hard clinical endpoints (CLD diagnoses from linked medical records), clear dose-response relationships, and rigorous mediation analysis; robust but observational design limits causal inference.
Reported
Sample size107363
CLD cases1888
CLD incidence proportion1.8%