Acta Naturae

OCT 27, 2026 · JOURNAL ARTICLE

From dysfunction to differentiation: a new paradigm of T cell exhaustion

Acta Naturae

CD8+ T cell exhaustion is the loss of certain functions typical of cytotoxic lymphocytes. CD8+ cytotoxic T cells originate from naive CD8+ T cells upon antigen exposure. Chronic or

OCT 27, 2026 · JOURNAL ARTICLE

A novel targeted conjugate for photodynamic therapy of HER2-positive cancer

Acta Naturae

Low selectivity against cancer cells remains one of the key challenges of many modern photosensitizers. To enhance the selectivity of the action and the effectiveness of tumor ther