Acs Nano

NOV 2, 2026 · JOURNAL ARTICLE

Design of Water-Resistant, Food-Grade Microneedles for Fish Injection and Underwater Cargo Delivery

Acs Nano

Abstract Aquatic foods provide around 15% of consumed animal-derived protein worldwide and aquaculture now supplies most of it. But the industry faces significant challenges in dis

NOV 2, 2026 · JOURNAL ARTICLE

Intracellular Polymerization-Induced Self-Assembly of Peptide Nanosheets for Inflammatory Breast Cancer Therapy

Acs Nano

Abstract Inflammatory breast cancer (IBC) is a highly aggressive breast cancer subtype characterized by diffuse, biologically invasive growth and poorly defined tissue boundaries,

OCT 27, 2026 · JOURNAL ARTICLE

Temporal Dosing Tunes Glutathione Gradient across Liver-Blood-Tumor Axes to Boost the Chemotherapeutic Potency of Prodrug Nanoassemblies

Acs Nano

Abstract Redox-responsive prodrug nanodelivery systems hold immense promise in cancer therapy, offering advantages of improved pharmacokinetics, enhanced tumor selectivity, and inc

OCT 24, 2026 · JOURNAL ARTICLE

All-in-One Mitochondria-Targeted Iron-Based MOF “Nanomissiles” for Synergistically Potentiated Tumor Ferroptosis, Dual Phototherapy, and Chemotherapy

Acs Nano

Abstract Pronounced heterogeneity and adaptability of tumors inherently curtail monotherapeutic efficacy, necessitating rationally integrated multimodal regimens that enable precis

OCT 22, 2026 · JOURNAL ARTICLE

Poly(acrylamido) PEG-Alternative Lipids Rescue mRNA Efficacy during Repeated Dosing and Enhance Immune Cell Delivery

Acs Nano

Abstract Following the successes of the messenger RNA (mRNA) lipid nanoparticle (LNP) vaccines against COVID-19, mRNA-LNPs are being explored for varied multidose applications incl

OCT 13, 2026 · JOURNAL ARTICLE

Turn Shield into Sword: Pathological Hydroxyapatite-Targeting Micelles Drive Metabolic Stress-Induced Autophagy Dysfunction for Bone Metastasis Therapy

Acs Nano

Abstract Bone metastasis remains a major clinical challenge in advanced breast cancer because therapeutic efficacy is limited by poor lesion targeting and systemic toxicity. Moreov

OCT 10, 2026 · JOURNAL ARTICLE

Membrane-Anchored Dual-Targeting Aptamer Engagers for Programmable T Cell Redirection in Solid and Hematological Cancers

Acs Nano

Abstract Inefficient immune synapse formation limits the therapeutic efficacy of T cell-based immunotherapy in both solid tumors and hematological malignancies. Here, we report a f

OCT 10, 2026 · JOURNAL ARTICLE

Oncolytic Virus-like Nanoparticle Targets the Golgi Apparatus via Sphingomyelin

Acs Nano

Abstract The Golgi apparatus (GA) has emerged as a promising target for cancer therapy. Commonly, therapeutics are guided to the GA by recognizing specific receptors on the GA memb