Loading
Life sciences · Interventional Study
ClinicalTrials.gov · September 24, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Interventional Study.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT05349877). This is a study registration, not published results. Lead sponsor: Pontificia Universidade Católica do Rio Grande do Sul. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 306 participants (ACTUAL). Conditions: Depression, Anxiety, Psychological Distress, Social Phobia, Post Traumatic Stress Disorder, Suicidal Ideation, Sex, Unsafe, Discrimination, Social, Behavior, Risk, Self Esteem. Interventions: BEHAVIORAL: Expressive writing; BEHAVIORAL: Self-affirmation; BEHAVIORAL: Placebo. Primary outcome measures: Change from baseline depression at 3 and 6 moths after the intervention. , Baseline (T0), one week after the intervention (T1), three months after the intervention (T2), and six the intervention (T3).; Change from baseline anxiety at 1 week, and 3 and 6 moths after the intervention. , Baseline (T0), one week after the intervention (T1), three months after the intervention (T2), and six the intervention (T3).; Change from baseline social phobia at 1 week, and 3 and 6 moths after the intervention. , Baseline (T0), one week after the intervention (T1), three months after the intervention (T2), and six the intervention (T3).; Change from baseline post-traumatic stress at 1 week, and 3 and 6 moths after the intervention. , Baseline (T0), one week after the intervention (T1), three months after the intervention (T2), and six the intervention (T3).; Change from baseline on suicide ideation at 3 and 6 moths after the intervention. , Baseline (T0), three months after the intervention (T2), and six the intervention (T3).; Change from baseline on substance use at 3 and 6 moths after the intervention. , Baseline (T0), three months after the intervention (T2), and six the intervention (T3).; Change from baseline on sex risk behaviors at 3 and 6 moths after the intervention. , Baseline (T0), three months after the intervention (T2), and six the intervention (T3).. Brief summary: Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination and internalized homophobia), mediated by resilience strategies, can lead to mental health or illness. Sexual and gender minorities (SGM) face stigma and discrimination aggravating multiple aspects of their lives: from school drop-out to halting health care access. SGM reveal avoiding medical assistance for fear of discrimination while health professionals disclose feeling unprepared to handle SGM health needs. There are two main challenges: 1) developing specific psychological interventions to reduce the impact of stigma and discrimination on SGM' mental health; and 2) training public health professionals to properly address SGM needs. Therefore, the present trial aims to assess the efficacy of a brief, self-guided, on-line, asynchronous and unsupervised psychological intervention in improving SGM' mental health.