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Life sciences · Interventional Study
ClinicalTrials.gov · October 29, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05325944). This is a study registration, not published results. Lead sponsor: Northwestern University. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 90 participants (ACTUAL). Conditions: Nonsuicidal Self Injury, Suicidal Ideation, Depression, Anxiety. Interventions: BEHAVIORAL: Self-guided digital intervention for NSSI; BEHAVIORAL: Digital intervention for NSSI with coaching; BEHAVIORAL: Active control. Primary outcome measures: Alexian Brothers Assessment of Self-Injury - Methods Checklist , 16 weeks; Alexian Brothers Urges to Self-Injure Scale , 16 weeks. Brief summary: This is a feasibility trial of a digital mental health intervention aimed at young adults (ages 18-25) with nonsuicidal self-injury and who are not currently engaged in mental health treatment. We will pilot three arms: a self-guided DMHI, the DMHI with low-intensity coaching, or an active control which will involve the delivery of non-interactive psychoeducational content via the same app interface. The primary goals of this project are to evaluate the feasibility of the intervention and trial procedures in preparation for a fully-powered randomized-controlled trial.