Life sciences · Interventional Study
ClinicalTrials.gov · October 13, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05027789). This is a study registration, not published results. Lead sponsor: University of California, Davis. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 263 participants (ESTIMATED). Conditions: Memory Disorders, Cognitive Impairment. Interventions: BEHAVIORAL: Self-Guided; BEHAVIORAL: Structured Group. Primary outcome measures: Logical Memory , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Free and Cued Selective Reminding Test (FCRT) , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Digit Span , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Trail Making , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Digit Symbol , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Verbal Fluency , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Royal Prince Alfred Prospective Memory Test , Change in assessment scores from baseline to 6-months, 12-months, and 18-months; Everyday Function , Change in assessment scores from baseline to 6-months, 12-months, and 18-months. Brief summary: The purpose of this research is to determine if training in memory support aids and healthy lifestyle activities (physical exercise, mentally stimulating activities and stress management) can have a positive effect on memory, thinking, and activities that people do every day. Participation in this study will involve being placed into one of two groups: a Self-Guided Intervention Group or a Structured Intervention Group. Both groups will be asked to attend group sessions in which they will be provided education on memory support strategies and lifestyle changes. The Structured Intervention Group will also be provided with an iPad and a digital application (called EMMA) to track their activity. Study participation involves a 6-month intervention and completing outcome measures at 4 different time points for up to a year.