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Life sciences · Interventional Study
ClinicalTrials.gov · October 16, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT06032104). This is a study registration, not published results. Lead sponsor: University of California, Davis. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 28 participants (ACTUAL). Conditions: Colorectal Polyp, Obesity. Interventions: DIETARY_SUPPLEMENT: Dry beans; DIETARY_SUPPLEMENT: Usual diet. Primary outcome measures: Compliance with the bean smoothie intervention , 2-4 weeks prior to colonoscopy, till 2-12 weeks after colonoscopy; Tolerance to the bean smoothie intervention , 2-4 weeks prior to colonoscopy, till 2-12 weeks after colonoscopy; Effect of the bean smoothie intervention on serum biomarkers of health , 2-4 weeks prior to colonoscopy, till 2-12 weeks after colonoscopy; Change in fecal abundance of microbiome genes with bean smoothie intervention , 2-4 weeks prior to colonoscopy, till 2-12 weeks after colonoscopy; Change from baseline in the fecal and serum metabolome with bean smoothie intervention , 2-4 weeks prior to colonoscopy, till 2-12 weeks after colonoscopy; Impact of bean intervention on colonic tissue RNA markers of health , 2-4 weeks prior to colonoscopy till colonoscopy. Brief summary: Beans are a forgotten staple food that shows promise in improving health. The goal of this study is to look at how bean supplementation affects metabolic and bowel health. In the long-term, the investigators believe this research will lead to a better understanding of the impact of beans on bowel health. The investigators also hope that this research study will help us understand ways to improve human diet and prevent colon cancer in the future.