Life sciences · Phase 4 Trial
ClinicalTrials.gov · October 9, 2026
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Phase 4 Trial.
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Registry record from ClinicalTrials.gov (NCT07351864). This is a study registration, not published results. Lead sponsor: Mansoura University. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: PHASE4. Study type: INTERVENTIONAL. Enrollment: 60 participants (ESTIMATED). Conditions: Heart Failure. Interventions: DRUG: Finerenone; DRUG: dapagliflozine. Primary outcome measures: Cardiovascular Mortality and Heart Failure Hospitalization , Up to 12 weeks (assessed at Baseline, Week 4, and Week 12). Brief summary: The goal of this clinical study is to evaluate whether adding finerenone to standard treatment with a sodium-glucose cotransporter-2 (SGLT2) inhibitor provides additional benefits in patients with heart failure. The main question this study aims to answer is whether the combination of finerenone and an SGLT2 inhibitor improves clinical outcomes and is safe compared to treatment with an SGLT2 inhibitor alone. Participants will receive standard therapy with an SGLT2 inhibitor, with or without the addition of finerenone and will be followed to assess clinical outcomes and safety.