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Parvovirus B19 Infection Studies / Herpesvirus Infections and Treatments · Journal article
Journal of Advances in Microbiology · September 4, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a descriptive seroprevalence survey of HSV-2 antibodies among 162 pregnant women in a single Nigerian hospital setting, reporting low IgG positivity (3.1%) and minimal IgG/IgM (0.6%), with no detectable viral DNA in positive samples. The study provides local epidemiological data but lacks a comparator group, clinical outcomes, or mechanistic insight and should not inform clinical decision-making without replication in larger or diverse populations.
Cross-sectional, hospital-based survey. Pregnant women attending antenatal care in hospitals within Bauchi Metropolis, Bauchi State, Nigeria. No further eligibility criteria, exclusion criteria, or demographic details provided.. n = 162. Bauchi Metropolis, Bauchi State, Nigeria; specific hospital names and number of sites not stated..
5 of 162 (3.1%) pregnant women were positive for HSV-2 IgG antibodies 1 of 162 (0.6%) pregnant women were positive for HSV-2 IgG/IgM antibodies No amplified HSV-2 DNA fragments detected in the five analysed samples
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This local survey documents a relatively low HSV-2 seroprevalence in the studied pregnant population, but the small size, single-centre setting, and absence of clinical outcomes or comparison data limit its utility for guiding clinical practice or informing infection control decisions at other sites.
A small, single-centre cross-sectional seroprevalence survey with no comparator group, reporting descriptive findings on HSV-2 antibody prevalence in a local pregnant population without intervention or mechanistic depth.
As stated by the source record.
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This local survey documents a relatively low HSV-2 seroprevalence in the studied pregnant population, but the small size, single-centre setting, and absence of clinical outcomes or comparison data limit its utility for guiding clinical practice or informing infection control decisions at other sites.
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Background: Herpes simplex virus type-2 (HSV-2) belongs to the Alphaherpesvirinae subfamily within the Herpesviridae family and causes genital herpes. Genital HSV infection is a pressing public health issue, with its global prevalence rising significantly over the past 40 years. Pregnancy is a distinct phase of life experienced by many women. Methods: This was a cross-sectional, hospital-based study conducted among 162 pregnant women who were screened for herpes simplex virus type-2 (HSV-2). Sociodemographic characteristics, risk factors, and clinical characteristics were analysed in relation to HSV-2 test outcomes. Associations were determined using the chi-square test, with statistical significance set at p < 0.05. Results: A total of 162 blood samples were collected and analysed in the laboratory. The findings revealed that 5 (3.1%) were positive for HSV-2 IgG, and 1 (0.6%) was positive for HSV-2 IgG/IgM. IgG antibodies usually indicate past or latent infection, while IgM antibodies suggest recent or acute infection. The absence of amplified DNA fragments in the five analysed samples indicated that HSV-2 genetic material was not detected at the time of analysis. Conclusion: The findings of this study indicate a relatively low burden of HSV-2 infection among the pregnant women examined, especially when compared with several Nigerian and African studies reporting higher seroprevalence rates. The presence of both IgG (3.1%) and IgG/IgM (0.6%) antibodies confirms that HSV-2 infection still occurs among pregnant women. These findings highlight the importance of integrating molecular diagnostics with serological screening and clinical evaluation to better understand the epidemiology of HSV-2 infection during pregnancy. The aim of this study was to determine the molecular characteristics of herpes simplex virus type-2 (HSV-2) among pregnant women attending some hospitals within Bauchi, Bauchi State, Nigeria.
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